Associate Professor of Chemistry
Temple 448
417/836-8567
E-mail: DeanCuebas@missouristate.edu
Office Hours:  MW  9:00 - 10:00; R  11:00 - noon; and by appointment

PhD, City University of  New York, 1987
Biochemistry

 

Classes for Fall 2009

CHM 105  Fundamentals of Chemistry
CHM 353   Introduction to Biochemistry Laboratory

Research Interests - Biochemistry, Lipid Metabolism, Enzymology

My research interests include various aspects of intermediary lipid metabolism in rat liver peroxisomes. More specifically, I am currently interested in the enzymological details involved in the conversion of cholesterol into bile acids. Research goals are to purify and characterize the enzymes involved in the latter part of this pathway, design active site- directed inhibitors to these enzymes, and thereby study the regulation of this process in isolated rat liver peroxisomes. Additionally, the stereochemistry of this metabolic sequence of reactions is not well understood and this aspect will also be addressed. The scope of this work would provide students opportunities to perform laboratory research involving synthetic organic chemistry, enzymology, intermediary metabolism, protein purification and characterization, and various forms of chromatography.

Professional Affiliations

American Chemical Society
American Society for Biological Chemists and Molecular Biologists
Sigma Xi